Microcap Ledger

Tickers · $XLO

Xilio Therapeutics, Inc. $XLO

By Microcap Ledger desk · CIK 0001840233

Facts as of . Built from SEC filings and our own data. Small caps move fast; check the latest filings.

Snapshot

Exchange
Nasdaq Capital Market
Sector
Pharmaceutical Preparations
Headquarters
Waltham, MA
Fiscal year end
December 31
Shares outstanding
5,782,511 [10-K 2026-03-23]
as of 2026-03-18

Sources: [10-K 2026-03-23]

What the company doesAI summary of filing

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies designed to selectively activate within the tumor microenvironment to treat cancer. The company uses proprietary masking technology to design biologics that remain inactive until reaching tumors, where tumor-specific proteases activate them to generate localized anti-tumor immune responses while minimizing systemic side effects. Xilio is advancing multiple wholly-owned programs (including XTX501, a bispecific PD-1/masked IL-2; masked T cell engagers targeting PSMA/STEAP1 and CLDN18.2; and efarindodekin alfa, a masked IL-12) alongside collaborative programs with AbbVie and Gilead. The company is pre-revenue and has not yet reported clinical data demonstrating product efficacy sufficient for regulatory approval. [10-K 2026-03-23]

Segments: XTX501 (bispecific PD-1/masked IL-2), Masked T Cell Engager Programs, Efarindodekin alfa (masked IL-12), Vilastobart (masked anti-CTLA-4)

Financial health

From XBRL company facts (USD)
PeriodRevenueNet incomeOperating cash flowCashFiling
6 months to Jun 2026$31.34M−$15.90M −$41.10M$136.04M[10-Q 2026-08-12]
FY ended Dec 2025$43.77M−$35.04M −$4.99M$137.53M[10-K 2026-03-23]
FY ended Dec 2024$6.34M−$58.24M −$18.38M$55.29M[10-K 2026-03-23]
Quarterly cash burn
−$20.55M
Cash runway Estimate
~19.9 months

Estimate: cash at the end of the period (6 months to Jun 2026) divided by the average monthly operating cash outflow over that period. Ignores any cash raised or spent since, and any financing.

Capital structure and dilution

Summary only. How these instruments work: Dilution & financing desk.

Share count
DateShares outstandingFiling
2024-05-1036,912,373[10-Q 2024-05-14]
2024-08-0143,952,491[10-Q 2024-08-08]
2024-11-0143,958,074[10-Q 2024-11-07]
2025-03-0351,773,717[10-K 2025-03-11]
2025-05-0551,782,273[10-Q 2025-05-08]
2025-08-0851,827,910[10-Q 2025-08-14]
2025-11-1152,500,328[10-Q 2025-11-13]
2026-03-185,782,511[10-K 2026-03-23]
Shelf registration
S-3 filed 2026-05-12; declared effective 2026-05-29 [S-3 2026-05-12]

Listing status

Current status: 3 Form 8-K Item 3.01 filing(s) in the last 24 months, most recent 2025-10-03. Item 3.01 covers delisting notices, failures to meet a listing rule and listing transfers; read the filing for which one.

DateEventDetailsDeadlineFiling
2025-10-038-K Item 3.01Notice of delisting or failure to satisfy a continued listing rule or standard; or transfer of listing—[8-K 2025-10-03]
2025-08-288-K Item 3.01Notice of delisting or failure to satisfy a continued listing rule or standard; or transfer of listing—[8-K 2025-08-28]
2025-04-088-K Item 3.01Notice of delisting or failure to satisfy a continued listing rule or standard; or transfer of listing—[8-K 2025-04-08]

More on deficiency notices and uplistings: Listing status desk.

Catalysts and calendar

Facts as of . Small caps move fast; check the latest filings.