Microcap Ledger

Tickers · $FULC

Fulcrum Therapeutics, Inc. $FULC

By Microcap Ledger desk · CIK 0001680581

Facts as of . Built from SEC filings and our own data. Small caps move fast; check the latest filings.

Snapshot

Exchange
Nasdaq Global Market
Sector
Pharmaceutical Preparations
Headquarters
Cambridge, MA
Fiscal year end
December 31
Shares outstanding
76,297,257 [10-Q 2026-07-30]
as of 2026-07-23

Sources: [10-K 2026-02-24]

What the company doesAI summary of filing

Fulcrum Therapeutics is a clinical-stage biopharmaceutical company developing small molecules to treat genetically defined rare diseases. Its lead product candidate, pociredir, is an oral small molecule in clinical development for sickle cell disease, designed to induce fetal hemoglobin; the company completed a Phase 1b trial and plans to initiate a registration-enabling trial in the second half of 2026. The company is pre-revenue and relies on its proprietary discovery approach to identify cellular drug targets that may modulate gene expression, with a secondary focus on exploring additional mechanisms for sickle cell disease and a preclinical program in prostate cancer. Fulcrum finances its operations through capital raises and has an accumulated deficit of $594.3 million as of December 31, 2025. [10-K 2026-02-24]

Segments: Pociredir (sickle cell disease), FTX-6274 (prostate cancer, preclinical)

Financial health

From XBRL company facts (USD)
PeriodRevenueNet incomeOperating cash flowCashFiling
6 months to Jun 2026—−$45.07M −$34.79M$48.47M[S-4 2026-09-02]
FY ended Dec 2025$0.00−$74.88M −$60.06M$197.53M[S-4 2026-09-02]
FY ended Dec 2024$80.00M−$9.72M −$2.22M$58.21M[S-4 2026-09-02]
Quarterly cash burn
−$17.39M
Cash runway Estimate
~8.4 months

Estimate: cash at the end of the period (6 months to Jun 2026) divided by the average monthly operating cash outflow over that period. Ignores any cash raised or spent since, and any financing.

Capital structure and dilution

Summary only. How these instruments work: Dilution & financing desk.

Share count
DateShares outstandingFiling
2024-11-0653,938,661[10-Q 2024-11-13]
2025-02-1853,979,306[10-K 2025-02-25]
2025-04-2453,979,306[10-Q 2025-05-01]
2025-07-2254,091,588[10-Q 2025-07-29]
2025-10-2254,118,438[10-Q 2025-10-29]
2026-02-1766,600,209[10-K 2026-02-24]
2026-04-2066,633,321[10-Q 2026-04-27]
2026-07-2376,297,257[10-Q 2026-07-30]
Shelf registration
S-3 filed 2024-02-27; declared effective 2024-04-25 [S-3 2024-02-27]

Listing status

Current status: No Form 8-K Item 3.01 (listing notice) filings in the last 24 months, as of 2026-10-11.

More on deficiency notices and uplistings: Listing status desk.

Who owns it

Recent Form 4 transactions
DateInsiderTypeSharesPriceFiling
2026-07-17Tang Kevinbuy50,945$3.52[4 2026-07-20]
2026-07-16Tang Kevinbuy116,671$3.56[4 2026-07-20]
2026-07-15Tang Kevinbuy107,377$3.56[4 2026-07-15]
2026-07-14Tang Kevinbuy53,651$3.56[4 2026-07-15]
2026-07-14Tang Kevinbuy75,952$3.58[4 2026-07-15]
2026-07-13Tang Kevinbuy12,966$3.54[4 2026-07-15]

Catalysts and calendar

Facts as of . Small caps move fast; check the latest filings.