Microcap Ledger

Tickers · $ALEC

Alector, Inc. $ALEC

By Microcap Ledger desk · CIK 0001653087

Facts as of . Built from SEC filings and our own data. Small caps move fast; check the latest filings.

Snapshot

Exchange
Nasdaq Global Select Market
Sector
Biological Products, (No Diagnostic Substances)
Headquarters
South San Francisco, CA
Fiscal year end
December 31
Shares outstanding
111,656,919 [10-Q 2026-08-06]
as of 2026-07-31

Sources: [10-K 2026-02-25]

What the company doesAI summary of filing

Alector is a clinical-stage biotechnology company developing therapies for neurodegenerative diseases. The company's lead candidate, nivisnebart, is a monoclonal antibody designed to elevate progranulin levels in the brain for the treatment of Alzheimer's disease and is currently in a Phase 2 clinical trial conducted with partner GlaxoSmithKline (GSK), with whom Alector shares development costs and potential profits. Alector is also advancing a portfolio of preclinical programs, including antibody therapies for amyloid-beta and glucocerebrosidase deficiency, and siRNA therapeutics targeting tau, alpha-synuclein, and NLRP3, all leveraging its proprietary Alector Brain Carrier (ABC) blood-brain barrier delivery platform. The company does not currently generate revenue from product sales and relies on third-party manufacturers and its partnership with GSK for development and commercialization. [10-K 2026-02-25]

Segments: Nivisnebart (PGRN-elevating antibody), AL137 (anti-amyloid beta antibody), AL050 (GCase enzyme replacement therapy), ABC-enabled siRNA programs (tau, alpha-synuclein, NLRP3)

Financial health

From XBRL company facts (USD)
PeriodRevenueNet incomeOperating cash flowCashFiling
6 months to Jun 2026$4.37M−$45.92M −$84.03M$59.91M[10-Q 2026-08-06]
FY ended Dec 2025$21.05M−$143.00M −$184.03M$65.80M[10-K 2026-02-25]
FY ended Dec 2024$100.56M−$119.00M −$229.91M$33.02M[10-K 2026-02-25]
Quarterly cash burn
−$42.02M
Cash runway Estimate
~4.3 months

Estimate: cash at the end of the period (6 months to Jun 2026) divided by the average monthly operating cash outflow over that period. Ignores any cash raised or spent since, and any financing.

Capital structure and dilution

Summary only. How these instruments work: Dilution & financing desk.

Share count
DateShares outstandingFiling
2024-11-0197,932,605[10-Q 2024-11-06]
2025-02-2199,085,888[10-K 2025-02-26]
2025-05-0299,992,600[10-Q 2025-05-08]
2025-08-01101,212,329[10-Q 2025-08-07]
2025-10-31109,151,472[10-Q 2025-11-06]
2026-02-20110,362,581[10-K 2026-02-25]
2026-05-01111,025,187[10-Q 2026-05-07]
2026-07-31111,656,919[10-Q 2026-08-06]
Shelf registration
S-3 filed 2026-03-12; declared effective 2026-04-30 [S-3 2026-03-12]

Listing status

Current status: No Form 8-K Item 3.01 (listing notice) filings in the last 24 months, as of 2026-10-11.

More on deficiency notices and uplistings: Listing status desk.

Who owns it

Recent Form 4 transactions
DateInsiderTypeSharesPriceFiling
2026-09-04Wong-Sarad Gracesell3,625$2.51[4 2026-09-04]
2026-09-03Wong-Sarad Gracesell5,165$2.67[4 2026-09-04]
2026-09-03Berkley Neil Lindsaysell29,251$2.66[4 2026-09-04]
2026-09-03Rosenthal Arnonsell72,606$2.66[4 2026-09-04]
2026-09-02Wong-Sarad Gracesell656$2.75[4 2026-09-04]
2026-08-19Rosenthal Arnonother1,050,000—[4 2026-08-21]
2026-08-19Rosenthal Arnonother350,000—[4 2026-08-21]
2026-08-19Rosenthal Arnonother350,000—[4 2026-08-21]
2026-08-19Rosenthal Arnonother350,000—[4 2026-08-21]
2026-07-09Wong-Sarad Gracegrant20,000—[4 2026-07-09]
2026-06-17Yaffe Kristinegrant28,700—[4 2026-06-17]
2026-06-17Scheller Richard Hgrant28,700—[4 2026-06-17]

Catalysts and calendar

Facts as of . Small caps move fast; check the latest filings.